Wonderful-Wednesdays

Repository to hold the data and materials for the Wonderful Wednesdays webinar series https://www.psiweb.org/sigs-special-interest-groups/visualisation/welcome-to-wonderful-wednesdays

View the Project on GitHub VIS-SIG/Wonderful-Wednesdays

Visualizing Benefit-Risk Profiles in Drug Development

Background: The assessment of benefit-risk profiles is crucial in drug development and regulatory decision-making. Effective visualization of these profiles can greatly enhance understanding and communication among stakeholders. This challenge is inspired by the work presented in the paper: “Planning Benefit-Risk Assessments Using Visualizations” by Colopy MW, Gakava L, Chen C. Ther Innov Regul Sci. 2023 Nov;57(6):1123-1135. doi: 10.1007/s43441-023-00563-9. Epub 2023 Sep 8. PMID: 37682462.

In their paper, Colopy et al. emphasize the importance of proactive planning in benefit-risk assessments and propose various visualization techniques to facilitate this process. They present a series of visualizations that progress from analyzing the medical condition and current treatment options to assessing the investigational drug.

Data set: For this challenge, you will be working with a dataset (brdata.xlsx). The Excel spreadsheet contains two tabs:

The Challenge: Create a visualization (or set of visualizations) using the provided dataset to effectively communicate the benefit-risk profiles of the drugs. Your visualization should aim to address one or more of the following aspects:

There are no strict restrictions on the type of visualization or the specific questions you choose to address. Your goal is to create a visualization that provides meaningful insights into the benefit-risk profiles and facilitates decision-making in drug development.

Submission Requirements:

Reference: Colopy MW, Gakava L, Chen C. Planning Benefit-Risk Assessments Using Visualizations. Ther Innov Regul Sci. 2023 Nov;57(6):1123-1135. doi: 10.1007/s43441-023-00563-9. Epub 2023 Sep 8. PMID: 37682462.