Background

The PRIMUM study aimed to improve medication appropriateness in elderly patients with multimorbidity. A complex intervention involving general practitioners (GPs) and their healthcare assistants (HCA) was developed and compared to usual care.

Challenge

Check for a treatment effect on the MAI score after the intervention. Visualize the effect of adjusting the treatment effect for the MAI score at baseline.

Data

The simulated data set is based on the PRIMUM study (Muth et al., 2016). The following variables can be found in the data set:

• mai: MAI-Score after the intervention
• gr: group variable
• base.mai: MAI score at baseline

The data can be found here.

Reference

Muth, C., Harder, S., Uhlmann, L., Rochon, J., Fullerton, B., Guethlin, C., Erler, A., Beyer, M., van den Akker, M., Perera, R., Knottnerus, A., Valderas Martinez, J., Gerlach, F.A., Haefeli, W.E. (2016). Pilot study to test the feasibility of a trial design and complex intervention on PRIoritising MUltimedication in Multimorbidity in general practices (PRIMUMpilot). BMJ Open 6:e011613